抗BCL2L1抗体(anti-BCL2L1antibody)
抗BCL2L1抗体(anti-BCL2L1antibody)
产品价格:¥1900.00(人民币)
  • 规格:完善
  • 发货地:湖北武汉市
  • 品牌:
  • 最小起订量:1
  • 免费会员
    会员级别:试用会员
    认证类型:企业认证
    企业证件:通过认证

    商铺名称:武汉菲恩生物科技有限公司

    联系人:王先生(先生)

    联系手机:

    固定电话:

    企业邮箱:3495998903@qq.com

    联系地址:武汉市江夏区高新大道818号高科医疗器械园B9栋

    邮编:430206

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    商品详情
      产品参数
      品牌菲恩生物
      适用范围仅供科研使用
      规格100μg
      加工定制
      验证应用ELISA
      IHC
      IP
      IF
      WB
      宿主
      适应种属人源,销售
      可售卖地全国
      材质液体

        名称:抗BCL2L1抗体(anti-BCL2L1 antibody)

        货号:FNab00842

        适应种属:人源,小鼠

        规格:100ug(微克)

        状态:液体

        纯化方法:免疫亲和纯化

        纯度:经sds-page分析,纯度大于95

        宿主:兔

        亚型:IgG

        存储:用添加了0.02叠氮化钠和50甘油的pbs溶解,ph值7.3,可在-20℃下保存12个月(避免反复冻融)

        免疫原:BCL2-like 1

        免疫原别称:BCL2L, BCLX

        分子量:30 kDa

        验证应用:ELISA, IHC, IP, IF, WB

        建议稀释比例:WB: 1:1000-1:6000; IP: 1:500-1:3000; IHC: 1:50-1:500; IF: 1:50-1:500

        克隆性:多克隆

        UniProt ID:Q07817

        背景介绍:Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel(VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter release and recovery, number of axonal mitochondria as well as size and number of synaptic vesicle clusters. During synaptic stimulation, increases ATP availability from mitochondria through regulation of mitochondrial membrane ATP synthase F(1)F(0) activity and regulates endocytic vesicle retrieval in hippocampal neurons through association with DMN1L and stimulation of its GTPase activity in synaptic vesicles. May attenuate inflammation impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785). Isoform Bcl-X(S) promotes apoptosis。

        Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab00842(BCL2L1 antibody) at dilution of 1:100。

        IP result of anti-BCL2L1(IP:FNab00842, 3ug; Detection:FNab00842 1:500) with K-562 cells lysate 8000 ug。

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